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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3X All Species: 16.36
Human Site: Y38 Identified Species: 25.71
UniProt: O00571 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00571 NP_001347.3 662 73243 Y38 S T A S K G R Y I P P H L R N
Chimpanzee Pan troglodytes Q6GVM6 660 73172 G36 G A S R A S K G R Y I P P H L
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 Y288 S T A S K G R Y I P P H L R N
Dog Lupus familis XP_861268 662 73195 Y38 S T A S K G R Y I P P H L R N
Cat Felis silvestris
Mouse Mus musculus Q62167 662 73083 Y38 S T A S K G R Y I P P H L R N
Rat Rattus norvegicus NP_001102328 659 72976 G36 G A S T A S K G R Y I P P H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 N32 Y I P P H L R N R E A S K G F
Chicken Gallus gallus NP_001025971 651 72031 G36 E G S A T S K G R Y I P P H L
Frog Xenopus laevis P24346 697 77284 D79 D G R M N G Y D R G G Y G S R
Zebra Danio Brachydanio rerio NP_571016 688 75828 H66 N G F V N G Y H D G R D N R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 R153 R R G G D W N R S G G G G G G
Honey Bee Apis mellifera XP_391829 701 78642 R81 E R E R D R D R G R G G S G Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 V32 R P S R T N Y V P P H L R S R
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 Y27 G G G G K S S Y V P P H L R S
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 G52 D A A P P M A G P N G L N N S
Conservation
Percent
Protein Identity: 100 91.3 70.1 99.8 N.A. 98.6 95.3 N.A. 95.9 91.2 82.2 76.3 N.A. 51.7 58 N.A. N.A.
Protein Similarity: 100 95.3 70.3 99.8 N.A. 99 97.1 N.A. 97.2 94.7 88 83.8 N.A. 63.4 70 N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 6.6 0 6.6 13.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 20 N.A. 6.6 20 13.3 26.6 N.A. 0 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 49.4 52
Protein Similarity: N.A. N.A. N.A. 64.6 65.2 64.8
P-Site Identity: N.A. N.A. N.A. 6.6 46.6 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 60 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 34 7 14 0 7 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 0 14 0 7 7 7 0 0 7 0 0 0 % D
% Glu: 14 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 20 27 14 14 0 40 0 27 7 20 27 14 14 20 7 % G
% His: 0 0 0 0 7 0 0 7 0 0 7 34 0 20 0 % H
% Ile: 0 7 0 0 0 0 0 0 27 0 20 0 0 0 0 % I
% Lys: 0 0 0 0 34 0 20 0 0 0 0 0 7 0 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 0 0 14 34 0 20 % L
% Met: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 0 0 0 14 7 7 7 0 7 0 0 14 7 27 % N
% Pro: 0 7 7 14 7 0 0 0 14 40 34 20 20 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 14 7 20 0 7 34 14 34 7 7 0 7 40 14 % R
% Ser: 27 0 27 27 0 27 7 0 7 0 0 7 7 14 14 % S
% Thr: 0 27 0 7 14 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 0 0 7 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 20 34 0 20 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _